Patent · US Active

Peptide vaccine using mimic molecules of amyloid β peptide

US8586706B2 · kind B2 · utility

1Cited by
0References
5Claims
0Family size

Assignee

Inventor

Key dates

Filing dateOct 22, 2008
Grant dateNov 19, 2013
Priority date—
Expiry dateAug 17, 2029

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention is intended to discover a peptide that induces production of an antibody specific for an abnormal amyloid β peptide from mimic peptides of the amyloid β peptide and to utilize the same as a vaccine or immunogen. This invention relates to a pharmaceutical composition containing a peptide consisting of 8 to 30 amino acid residues, wherein the peptide comprises at least one of an amino acid sequence represented by formula (I): Tyr-Gly-Thr-Lys-Pro-Trp-Met (SEQ ID NO: 28) (I), and an amino acid sequence represented by formula (II): Leu-Asp-Ile-Phe-Ala-Pro-Ile (SEQ ID NO: 29) (II); or a conjugate of such peptide and a carrier.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.