Patent · US Active

Stapled peptides and method of synthesis

US8586707B2 · kind B2 · utility

4Cited by

1References

5Claims

0Family size

Assignee

The Research Foundation of the State University of New York · US

Inventors

Qing Lin · San Diego, US
Mike R. Madden · Tonawanda, US

Key dates

Filing date	Sep 16, 2009
Grant date	Nov 19, 2013
Priority date	—
Expiry date	Jan 14, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K1/1136
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A method for preparing stapled peptides. The stapled peptides, including helical stapled peptides, are prepared according to a photochemically-based method, a [3+2] cycloaddition reaction. The helical stapled peptides exhibit increased helicity, thermal stability and cell permeability.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.