Use of biomarkers and therapeutic agents with surgical devices

US8591459B2 · kind B2 · utility

Assignee

• Ethicon Endo-Surgery, Inc. · US

Inventors

• Jeffrey W. Clymer · Mason, US
• Prasanna Malaviya · Huangpu District, CN
• Donna L. Korvick · Maineville, US
• Kevin L. Houser · Springboro, US
• Cory G. Kimball · Cincinnati, US
• Foster B. Stulen · Mason, US
• Frederick E. Shelton, IV · Hillsboro, US
• Chester O. Baxter, III · Loveland, US
• Taylor W. Aronhalt · Loveland, US

Key dates

• Filing date: Dec 17, 2010
• Grant date: Nov 26, 2013
• Expiry date: Dec 17, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61M2037/0007
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Biomarkers are collected and used to determine biological propensities of a patient, to determine the efficacy of medical devices, to select and administer therapeutic agents, to select medical devices, to make adjustments to medical devices, and/or to adjust surgical techniques. An apparatus includes a port to draw a biological fluid (e.g., a mist) from a surgical site. The apparatus includes a sensor having a cantilevered beam. The beam includes substances selected to attract certain biomarkers as the fluid is communicated across the beam. The same apparatus or another apparatus is used to administer a therapeutic agent based at least in part on collected biomarker data. The therapeutic agent delivery apparatus may include a device that is also used to create a wound at a surgical site. For instance, a harmonic surgical instrument may be used to both collect biomarkers and administer a therapeutic agent (e.g., gene therapy using sonoporation).