Recombinant carrier molecule for expression, delivery and purification of target polypeptides
US8591909B2 · kind B2 · utility
3Cited by
79References
13Claims
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Key dates
| Filing date | Apr 12, 2012 |
| Grant date | Nov 26, 2013 |
| Priority date | — |
| Expiry date | Apr 12, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/35
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Recombinant carrier molecules having amino acid sequences from thermostable enzymes and methods of use for expression, recovery and delivery of foreign sequences (peptides and polypeptides) produced in different systems (bacteria, yeast, DNA, cell cultures such as mammalian, plant, insect cell cultures, protoplast and whole plants in vitro or in vivo are provided. The recombinant carrier molecule using sequences from lichenase B (Lic B) were also made and used as part of carrier protein to express, recover and deliver a variety of target polypeptides of interest.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.