Patent · US Active

Tri-block copolymers for nanosphere-based drug delivery

US8591951B2 · kind B2 · utility

56Cited by

15References

15Claims

0Family size

Inventors

Joachim B. Kohn · South Plainfield, US
David Devore · Langhorne, US
Larisa Sheihet · Bound Brook, US
Robert Dubin · Beltsville, US

Key dates

Filing date	Jul 27, 2005
Grant date	Nov 26, 2013
Priority date	—
Expiry date	Apr 30, 2027

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC08G2261/126
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Biocompatible non-toxic triblock copolymers having an A-B-A structure wherein each A is a hydrophilic, biocompatible end block and the B middle block is a hydrophobic desaminotyrosyl tyrosine polycarbonate or polyarylate. The copolymers spontaneously self-assemble to form low critical aggregation concentration nanospheres having utility as delivery vehicles for hydrophobic biologically or pharmaceutically active compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.