High-content screening for drugs against cancer and age-related diseases
US8592147B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 12, 2006 |
| Grant date | Nov 26, 2013 |
| Priority date | — |
| Expiry date | Aug 1, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5011
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to methods for high-throughput screening for compounds that modulate cell growth or promoter activity. The invention provides the use of cell lines with properly regulated promoter-reporter expression, suitable for high-throughput screening. More particularly, the invention relates to such screening to identify compounds that affect cell growth and/or that modulate the effect of cell cycle arrest on the function of a promoter that is responsive to cell cycle inhibition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.