Enzyme detection device
US8592167B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Aug 26, 2008 |
| Grant date | Nov 26, 2013 |
| Priority date | — |
| Expiry date | May 10, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/37
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An enzyme detection device (1) for detecting the presence, in a sample, of an enzyme capable of modifying a provided substrate (10). The device (1) comprises a substrate which has a modification region (14) that is sensitive to modification by the enzyme from an unmodified state to a modified state. The device (1) further comprises a substrate recognition molecule (16) which binds the modification region (14) in either the modified or the unmodified state. The modification region 14 of the substrate is preferentially bound by the substrate recognition molecule (16) as compared with the enzyme when mixed. The device further comprises a detectable label (18) coupled to the substrate recognition molecule (17).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.