Use of periostin as a novel biomarker
US8592223B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 9, 2012 |
| Grant date | Nov 26, 2013 |
| Priority date | — |
| Expiry date | Aug 9, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/34
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides, in certain embodiments, a method of assaying an indicator of, and treating, renal injury or renal disease. The method entails assaying a urine sample for periostin, wherein the presence of periostin at an elevated level indicates the presence and/or degree of renal injury or renal disease. The method also involves prescribing, initiating, or altering prophylaxis or therapy for renal injury or renal disease. Also provided, are methods of determining progression of these conditions, as well as methods of determining subjects' response to treatment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.