Patent · US Active

Compounds and compositions as protein kinase inhibitors

US8592432B2 · kind B2 · utility

4Cited by
1References
9Claims
0Family size

Inventors

Key dates

Filing dateApr 3, 2009
Grant dateNov 26, 2013
Priority date
Expiry dateJan 18, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D487/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention provides novel pyrimidine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, c-ros oncogene (ROS), insulin-like growth factor (IGF-1R), and/or insulin receptor (InsR) or a combination thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.