Substituted pyrrolo[2,3-b]-pyridines and -pyrazines

US8592448B2 · kind B2 · utility

Assignee

• OSI Pharmaceuticals, LLC · US

Inventors

• Xin Chen · Lexington, US
• Melzhong Jin · Dix Hills, US
• Andrew Kleinberg · Roslyn Heights, US
• An-Hu Li · New York, US
• Mark J. Mulvihill · Melville, US
• Arno G. Steinig · East Northport, US
• Jing Wang · Acton, US

Key dates

• Filing date: Nov 19, 2009
• Grant date: Nov 26, 2013
• Expiry date: Feb 7, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of Formula I, as shown below and defined herein: (I) pharmaceutically acceptable salts, synthesis, intermediates, formulations, and methods of disease treatment therewith, including cancers mediated at least in part by Ron and/or Met.