Method for making antibody Fc-heterodimeric molecules using electrostatic steering effects
US8592562B2 · kind B2 · utility
268Cited by
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18Claims
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Assignee
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Key dates
| Filing date | Jan 6, 2009 |
| Grant date | Nov 26, 2013 |
| Priority date | — |
| Expiry date | Dec 4, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/526
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to methods of making Fc-heterodimeric proteins or polypeptides. The invention also relates to the Fc-heterodimeric proteins or polypeptides themselves, including the individual polypeptide components that comprise the heterodimer. Nucleic acids encoding such polypeptides, expression vectors, and host cells. Moreover, the invention relates to pharmaceutical compositions comprising one of more Fc-heterodimeric proteins or polypeptides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.