Triple reuptake inhibitors and methods of their use
US8592608B2 · kind B2 · utility
2Cited by
3References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 15, 2009 |
| Grant date | Nov 26, 2013 |
| Priority date | — |
| Expiry date | Dec 15, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are bicyclic compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders. Compounds provided herein inhibit uptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine (e.g., from the synaptic cleft) and modulate one or more monoamine transporter. Pharmaceutical formulations containing the compounds are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.