Methods for introducing a human gene into a marmoset embryo for making a transgenic marmoset
US8592643B2 · kind B2 · utility
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1References
5Claims
0Family size
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Key dates
| Filing date | Dec 9, 2008 |
| Grant date | Nov 26, 2013 |
| Priority date | — |
| Expiry date | Aug 22, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2999/007
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An object of the present invention is to provide a method for introducing a gene into an embryo for production of a human disease model primate animal using a non-human primate animal such as a marmoset. The present invention relates to a method for introducing a foreign gene into an early embryo of a non-human primate animal, which comprises placing early embryos of a non-human primate in a 0.2 M to 0.3 M sucrose solution, so as to increase the volume of the perivitelline spaces, and then injecting a viral vector containing a human foreign gene operably linked to a promoter into the perivitelline spaces of the early embryos.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.