System for and method of positioning cells and determining cellular activity thereof
US8594762B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 10, 2010 |
| Grant date | Nov 26, 2013 |
| Priority date | — |
| Expiry date | Aug 16, 2032 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/049
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A device for positioning at least one cell in at least one addressable position, the device comprising a substrate formed with at least one addressable pore and at least one channel embedded in the substrate and being in fluid communication with the at least one pore. The at least one pore and the at least one channel are designed and constructed such that an under-pressure formed in the at least one channel results in vacuum adherence of the at least one cell onto the at least one pore, such that a single cell is vacuum adhered onto a single pore. In one embodiment, the substrate is a non-conductive substrate and is further formed with one or more electrode structures, where each of the electrode structures is positioned in one of the pores. In an additional embodiment the device is designed locatable onto an organ, such as a brain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.