Patent · US Active

Mutated env sequence involved in the modulation of the immunosuppressive effect of viral proteins

US8597657B2 · kind B2 · utility

3Cited by

2References

17Claims

0Family size

Assignees

INSTITUT GUSTAVE ROUSSY · FR
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE · FR
UNIVERSITÉ PARIS CITÉ · FR

Inventors

Martial Renard · Paris, FR
Marianne Mangeney · Paris, FR
Thierry Heidmann · Paris, FR

Key dates

Filing date	Feb 17, 2012
Grant date	Dec 3, 2013
Priority date	—
Expiry date	Feb 17, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K7/06
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Mutated viral ENV proteins having mutations in the immunosuppressive domain (ISU) of the transmembrane subunit (TM) have decreased immunosuppressive activity with respect to the wild-type ENV protein. Pharmaceutical compositions that include the protein and nucleic acids coding for the protein are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.