Glycosylation of molecules

US8597906B2 · kind B2 · utility

Assignees

• Oxyrane UK Limited · GB
• VIB VZW · BE
• UNIVERSITEIT GENT · BE

Inventors

• Nico Luc Marc Callewaert · Aalter, BE
• Wouter Vervecken · Landskouter, BE
• Karen Jacqueline Marcel De Pourcq · Evergem, BE
• Steven Christian Jozef Geysens · Kruisem, BE
• Mouna Guerfal · Veltem-Beisem, BE

Key dates

• Filing date: Apr 26, 2011
• Grant date: Dec 3, 2013
• Expiry date: Apr 26, 2031

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/52
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described herein are methods and genetically engineered cells useful for producing an altered N-glycosylation form of a target molecule. Also described are methods and molecules with altered N-glycosylation useful for treating a variety of disorders such as metabolic disorders.