Mutant yeast strains capable of accumulating a large quantity of lipids
US8597931B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jul 8, 2009 |
| Grant date | Dec 3, 2013 |
| Priority date | — |
| Expiry date | Oct 7, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/6463
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The subject of the present invention is a novel mutant yeast strain, particularly a Yarrowia lipolytica strain, capable of accumulate a large quantity of lipids. The said strain does not express the GUT2 gene. According to one variant, the invention relates to mutant yeast strains, particularly Yarrowia lipolytica strains, which do not express the GUT2 gene and which furthermore do not carry out the β-oxidation of lipids. Preferably, the mutant strains which do not express the GUT2 gene and which furthermore do not carry out β-oxidation of lipids do not express the POX 2 through POX 5 genes, most preferably the POX 1 through 6 genes. The subject of the invention is also a method for producing the strains according to the invention and the use of the said strains in the production of lipids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.