Hepatocyte growth factor mimics as therapeutic agents

US8598118B2 · kind B2 · utility

Assignee

• WASHINGTON STATE UNIVERSITY · US

Inventors

• Joseph W. Harding · Pullman, US
• John W. Wright · Los Altos, US
• Caroline C. Benoist · Nashville, US
• Leen H. Kawas · Seattle, US
• Gary A. Wayman · Pullman, US

Key dates

• Filing date: Feb 15, 2013
• Grant date: Dec 3, 2013
• Expiry date: Feb 15, 2033

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Small molecule, peptidic hepatocyte growth factors mimics, which act as both mimetics and antagonists, have been generated. These molecules have been shown or predicted to have therapeutic potential for numerous pathologies including dementia, neurodegenerative disease, diabetes and metabolic syndrome, cancer, and defective wound healing.