Variants of C-type natriuretic peptide
US8598121B2 · kind B2 · utility
7Cited by
15References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 8, 2012 |
| Grant date | Dec 3, 2013 |
| Priority date | — |
| Expiry date | May 8, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides variants of C-type natriuretic peptide (CNP), pharmaceutical compositions comprising CNP variants, and methods of making CNP variants. The CNP variants are useful as therapeutic agents for the treatment of diseases responsive to CNP, including but not limited to bone-related disorders, such as skeletal dysplasias (e.g., achondroplasia), and vascular smooth muscle disorders (e.g., restenosis and arteriosclerosis).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.