Patent · US Active

Glycosylated indolocarbazoles, method for obtaining same and uses thereof

US8598132B2 · kind B2 · utility

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18Claims
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Key dates

Filing dateApr 6, 2009
Grant dateDec 3, 2013
Priority date
Expiry dateSep 13, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12P19/28
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Glycosylated indolocarbazoles, method for obtaining same and uses thereof. This invention relates to rebeccamycin and staurosporine derivatives obtained by fermentation of recombinant bacterial strains. The invention also relates to the methods used to obtain the recombinant strains and the production of rebeccamycin and staurosporine derivatives. The invention also relates to bacterial strains that are of use for the production of rebeccamycin and staurosporine derivatives. Lastly, the rebeccamycin and staurosporine derivatives described herein are applicable to the field of human health, specifically for manufacturing drugs that are of use in the treatment of tumour, neurological and inflammatory diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.