Polycyclic agents for the treatment of respiratory syncytial virus infections

US8598193B2 · kind B2 · utility

Assignee

• BIOTA SCIENTIFIC MANAGEMENT PTY LTD · AU

Inventors

• Silas Bond · Koo Wee Rup, AU
• Vanessa Anne Sanford · Alpharetta, US
• John Lambert · Melbourne, AU
• Chin Yu Lim · Clayton, AU
• Jeffrey Peter Mitchell · Melbourne, AU
• Alistair George Draffan · Melbourne, AU
• Roland Henry Nearn · Melbourne, AU

Key dates

• Filing date: Dec 24, 2004
• Grant date: Dec 3, 2013
• Expiry date: Aug 19, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of formula (I), and their use as in the treatment of infections involving viruses of the Pneumovirinae sub-family (RSV) are disclosed. In the formula ring (A) may be phenyl, pyridyl etc., (B—C) may be CH2—CH2 etc., (R1) may be phenyl and substituted forms thereof, (R2) may be assorted substituents.