Patent · US Active

Antagonists of the vanilloid receptor subtype 1 (VR1) and uses thereof

US8598220B2 · kind B2 · utility

1Cited by
5References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 28, 2009
Grant dateDec 3, 2013
Priority date
Expiry dateJul 27, 2031

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D493/10
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to compounds of formula (I)wherein variables X1, X2, Y, R1a, R1b, R2a, R2b, A1, A2, A3, and A4 are as defined in the description, and methods of use to treat pain, neuropathic pain, allodynia, pain associated with inflammation or an inflammatory disease, inflammatory hyperalgesia, bladder overactivity, and urinary incontinence.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.