Buccal drug delivery
US8603517B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 28, 2012 |
| Grant date | Dec 10, 2013 |
| Priority date | — |
| Expiry date | Nov 28, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A lozenge is provided that has stable pH and stable levels of active ingredient over time. It comprises a combination of (i) at least one gum and (ii) at least one non-crystallising sugar or non-crystallising sugar alcohol in a matrix designed for controlled buccal delivery of a drug. The lozenge also contains water and optional components selected from flavorings, taste masking agents, colorings, buffer components, pH adjusting agents, excipients, stabilizers and sweeteners. Methods of preparing the lozenge are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.