Anti-avian influenza virus agent, and product containing anti-avian influenza virus agent
US8603548B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 8, 2009 |
| Grant date | Dec 10, 2013 |
| Priority date | — |
| Expiry date | May 28, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An anti-avian influenza virus agent containing, as an active ingredient, a component obtained when a guava extract extracted from a guava with an extraction solvent consisting primarily of at least one of water and a hydrophilic organic solvent is subjected to fractionation by HPLC under specific conditions. The specific conditions include the use of an ODS column, the use of a water-methanol mixture having a methanol concentration of 20% as a mobile phase during a period until 15 minutes after applying the guava extract to the column, and the use of a water-methanol mixture having a methanol concentration of 40% as a mobile phase during a subsequent period of 15 to 30 minutes. Alternatively, the specific conditions further include the use of a water-methanol mixture having a methanol concentration of 60% as a mobile phase during a period of 30 to 45 minutes after applying the guava extract to the column. The component contained in the anti-avian influenza virus agent is eluted from the column in a period until 20 minutes after applying the guava extract to the column or in a subsequent period of 20 to 35 minutes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.