Derivatized peptide-conjugated (meth) acrylate cell culture surface and methods of making

US8603820B2 · kind B2 · utility

Assignee

• CORNING INCORPORATED · US

Inventors

• Arthur Winston Martin · Horseheads, US
• Shawn Michael O'Malley · Glenside, US
• Simon K. Shannon · Woodbury, US
• Christopher Bankole Shogbon · Corning, US
• Carl M. Truesdale · Corning, US
• Yue Zhou · Shanghai, CN

Key dates

• Filing date: May 19, 2010
• Grant date: Dec 10, 2013
• Expiry date: Sep 26, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2537/00
• WIPO field: Other special machines
• WIPO sector: Mechanical engineering

Abstract

A synthetic cell culture surface, prepared from a mixture of at least three (meth)acrylate monomers where one of the monomers has an N-hydroxysuccinimide moiety is provided, which supports the growth of cells including undifferentiated human embryonic stem cells in defined media. Methods for preparing the cell culture surface is also provided.