Patent · US Active

Modulating signal transduction pathways with 1-ethyl-3-[3-(1-methyl-1H-pyrazol-4-yl)-pyrido[2.3-B]pyrazine-6-yl]thiourea

US8604196B2 · kind B2 · utility

0Cited by

6References

21Claims

0Family size

Assignee

Aeterna Zentaris, Inc. · DE

Inventors

Matthias Gerlach · Wächtersbach, DE
Irene Seipelt · Offenbach, DE
Eckhard Guenther · Maintal, DE
Emmanuel Polymeropoulos · Frankfurt, DE
Tilmann Schuster · Großostheim, DE
Eckhard Claus · Frankfurt, DE

Key dates

Filing date	Jul 5, 2012
Grant date	Dec 10, 2013
Priority date	—
Expiry date	Jul 5, 2032

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A method of modulating one or more of ras-Raf-Mek-Erk signal transduction pathway, PI3K-Akt signal transduction pathway and SAPK signal transduction pathway with 1-ethyl-3-[3-(1-methyl-1H-pyrazol-4-yl)-pyrido[2,3-b]pyrazine-6-yl]thiourea, its geometric isomer, or its tautomer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.