Patent · US Active

Salt of proline derivative, solvate thereof, and production method thereof

US8604198B2 · kind B2 · utility

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8References
6Claims
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Key dates

Filing dateJul 29, 2011
Grant dateDec 10, 2013
Priority date
Expiry dateJul 29, 2031

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides 3-{(2S,4S)-4-[4-(3-methyl -1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2 -ylcarbonyl}thiazolidine (compound I) useful as a dipeptidyl peptidase-IV inhibitor, which has superior properties of stability and hygroscopicity, and reproducible crystal structure, and a production method thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.