Preparative separation/purification system
US8607620B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 2, 2007 |
| Grant date | Dec 17, 2013 |
| Priority date | — |
| Expiry date | Jul 17, 2029 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D15/24
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
After a target compound is captured by an adsorbent within a trap column (7) held by a column rack (8) in a substantially vertical position and the column is filled with water to wash its inside, dichloromethane is slowly introduced from an inlet end (7a) on the lower side by a pump (5). The water within the trap column (7) is pushed upward by dichloromethane and exits from an outlet end (7b), to be disposed of via a two-way selector valve (12) and a disposal passage (14). Dichloromethane elutes the captured target compound. Therefore, when the eluate, which initially consists of water, changes via an emulsion to dichloromethane, the eluate contains an adequately high concentration of target compound. At this point, the two-way valve (12) is switched to a preparative separation passage (13). As a result, a solution that is adequately free from water and yet contains the target compound can be collected into a collection container (17), and the target compound in solid forms can be quickly obtained.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.