Patent · US Active

Auristatin drug linker conjugates

US8609105B2 · kind B2 · utility

74Cited by

31References

46Claims

0Family size

Assignee

SEATTLE GENETICS, INC. · US

Inventors

Peter D. Senter · Seattle, US
Svetlana O. Doronina · Snohomish, US
Timothy Bovee · Seattle, US

Key dates

Filing date	Mar 18, 2009
Grant date	Dec 17, 2013
Priority date	—
Expiry date	Mar 18, 2030

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Drug Linker compounds and Drug Linker Ligand conjugates are provided that have auristatins linked via the C-terminus. The conjugates show efficacy without the need for a self-immolative group to release the drug.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.