Patent · US Active

Fusion protein mixture for inducing human pluripotent stem cell and preparation method there of

US8609373B2 · kind B2 · utility

6Cited by

1References

8Claims

0Family size

Assignee

Novoprotein Scientific (Shanghai) Inc. · CN

Inventors

Chen-Yu Liu · Taoyuan, TW
Lijun Cai · Miaocheng, CN
Jianfeng Ding · New York, US

Key dates

Filing date	Aug 12, 2010
Grant date	Dec 17, 2013
Priority date	—
Expiry date	Aug 12, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/35
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention provides the protein mixture including the fusion proteins of C-myc, SOX2, KLF4, OCT-4, wherein each protein comprises a protein transduction domain (PTD) and a small ubiquitin-like modifier (SUMO) fused with the said protein. The invention further provides the preparation method of the protein mixture and its use for inducing human pluripotent stem cell.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.