Patent · US Active

Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism

US8609396B2 · kind B2 · utility

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10Claims
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Key dates

Filing dateAug 28, 2009
Grant dateDec 17, 2013
Priority date
Expiry dateApr 2, 2031

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Y602/01001
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Disclosed herein are a microorganism strain capable of producing the L-methionine precursor O-acetyl homoserine in high yield and a method of producing O-acetyl homoserine using the same. The microorganism strain is a strain of Escherichia sp. in which an acetyl-CoA synthase gene (acs) and/or a pantothenate kinase gene (coaA) encoding a pantothenate kinase gene refractory to feedback inhibition by CoA is introduced and expressed.

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