Method for manufacturing a tissue-engineered construct
US8609415B2 · kind B2 · utility
8Cited by
2References
15Claims
0Family size
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Key dates
| Filing date | Feb 2, 2009 |
| Grant date | Dec 17, 2013 |
| Priority date | — |
| Expiry date | Jul 17, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2240/008
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Method for manufacturing a tissue-engineered construct, such as a heart valve, comprising the steps of providing a-cell-seeded scaffold in a bioreactor chamber which bioreactor chamber is divided by the cell-seeded scaffold into a first compartment and a second compartment, subjecting the cell-seeded scaffold to a flow of nutrient medium within the bioreactor chamber for developing the cell-seeded scaffold to a tissue structure and next to the tissue construct, applying a dynamic pressure difference to the developing tissue structure by the flow of nutrient medium to induce dynamic strain on the tissue structure.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.