Pharmaceutical compositions of benzodiazepines and method of use thereof
US8609651B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 27, 2007 |
| Grant date | Dec 17, 2013 |
| Priority date | — |
| Expiry date | Dec 14, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention includes benzodiazepine compositions formulated for intranasal administration, comprising a binary solvent system comprising a first solvent in which the benzodiazepine is soluble, the first solvent capable of penetrating nasal mucosal tissue, and a second solvent in which the benzodiazepine in less soluble. The compositions of the present invention may be used to treat a variety of disorders including, but not limited to, panic attacks, muscle spasms, anxiety, and seizures. In one aspect, the present invention relates to a fast-acting, clonazepam composition for transnasal administration that can be used for the treatment of seizure clusters.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.