Sensory-specific local anesthesia and prolonged duration local anesthesia
US8609733B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | May 19, 2009 |
| Grant date | Dec 17, 2013 |
| Priority date | — |
| Expiry date | Jan 21, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P23/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Combinations of charged local anesthetics with chemical permeation enhancers have been developed to give long duration block which is selective for sensory block over motor block. The duration of block is greatly prolonged by combining the local anesthetic with a permeation enhancer. The selectivity of sensory over motor block is provided by selecting the concentration of the local anesthetic and the permeation enhancer to provide selective permeability of the sensory and motor neurons to the enhancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.