Patent · US Active

Method for the preparation of erlotinib

US8609841B2 · kind B2 · utility

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3References

16Claims

0Family size

Assignee

F.I.S. Fabbrica Italiana Sintetici S.p.A. · IT

Inventors

Andrea Castellin · Rubano, IT
Ottorino De Lucchi · Montecchio Maggiore, IT
Andrea Caporale · Vicenza, IT

Key dates

Filing date	Oct 13, 2011
Grant date	Dec 17, 2013
Priority date	—
Expiry date	Oct 13, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D239/94
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

An alternative method for the preparation of Erlotinib through a new chemical reaction for the preparation of the 4-(3-aminophenyl)-2-methyl-3-butyn-2-ol key intermediate of formula (IV) according to the following scheme.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.