Immunizing composition and method for inducing an immune response against the β-secretase cleavage site of amyloid precursor protein
US8613928B2 · kind B2 · utility
1Cited by
6References
6Claims
0Family size
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Key dates
| Filing date | Dec 6, 2010 |
| Grant date | Dec 24, 2013 |
| Priority date | — |
| Expiry date | Feb 14, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/77
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to an immunizing composition containing an antigenic product such as a multiple antigen peptide system (MAPS) or a filamentous bacteriophage displaying an AβPP epitope spanning the β-secretase cleavage site of AβPP and a method for inducing an immune response against the β-secretase cleavage site of AβPP using this immunizing composition. The present invention is also directed to antibodies against the β-secretase cleavage site of AβPP and their use in a method for inhibiting the formation of amyloid β.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.