Method for treating ocular cancer
US8614192B2 · kind B2 · utility
1Cited by
2References
2Claims
0Family size
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Key dates
| Filing date | Jul 24, 2007 |
| Grant date | Dec 24, 2013 |
| Priority date | — |
| Expiry date | Aug 2, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
It has now been found that the p53 pathway is inactivated in ocular cancers such as retinoblastoma. As such, the present invention is a method for inducing ocular cancer cell death using a p53 activator. In particular embodiments, the p53 activator blocks the interaction between DM2 or DMX and p53. As the p53 activator induces ocular cancer cell death, a method for preventing or treating ocular cancer is also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.