RTP801L siRNA compounds and methods of use thereof
US8614311B2 · kind B2 · utility
0Cited by
32References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 12, 2012 |
| Grant date | Dec 24, 2013 |
| Priority date | — |
| Expiry date | Oct 12, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/343
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides chemically modified siRNA oligonucleotides that target RTP801L, compositions comprising same and to the use of such molecules to treat, inter alia, respiratory diseases including acute and chronic pulmonary disorders, eye diseases including glaucoma and ION, microvascular disorders, angiogenesis- and apoptosis-related conditions, and hearing impairments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.