Filamin A binding anti-inflammatory and analgesic

US8614324B2 · kind B2 · utility

Assignee

• Pain Therapeutics, Inc. · US

Inventors

• Lindsay Burns Barbier · Austin, US
• Hoau-Yan Wang · Philadelphia, US
• Nan-Horng Lin · Mundelein, US
• Andrei Blasko · San Bruno, US

Key dates

• Filing date: Mar 8, 2010
• Grant date: Dec 24, 2013
• Expiry date: Jun 11, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D498/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A compound or its pharmaceutically acceptable salt, optionally including both individual enantiomeric forms, a racemate, diastereomers and mixtures thereof, composition and method are disclosed that can provide analgesia and reduce inflammation. A contemplated compound has a structure that corresponds to Formula A, wherein the R group substituents, d, e, f, k, n, m, D, E, F, K, G, P, Q, W, and Z are defined within.