Patent · US Active

System for the noninvasive determination of tracer concentration in blood

US8617072B2 · kind B2 · utility

0Cited by

3References

18Claims

0Family size

Assignee

KONINIKLIJKE PHILIPS N.V. · NL

Inventors

Dragos-Nicolae Peligrad · Aachen, DE
Lothar Spies · Aachen, DE
Timo Paulus · Aachen, DE

Key dates

Filing date	May 20, 2005
Grant date	Dec 31, 2013
Priority date	—
Expiry date	Aug 25, 2028

Classification

Technology area (CPC G)Physics
CPC primaryG16H30/40
WIPO fieldMedical technology
WIPO sectorInstruments

Abstract

The invention relates to a general composite compartmental model and a compartmental analysis procedure to extract non-invasively the concentration (Cp) of the imaging agent in plasma (301), in metabolites (304, 504) and in blood elements (303) (like red cells, platelets, plasma protein etc.) from time signal curves measured within a reference tissue region (200). This is made possible by deploying an injection function (SINJ(t)) as input which models the amount of imaging agent administered to the patient as a function of time. The invention allows the presentation of the plasma input function to the medical practitioner without the need for invasively drawing blood samples.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.