Multimodal nanoparticles for non-invasive bio-imaging

US8617522B2 · kind B2 · utility

Assignee

• University of Florida Research Foundation, INC. · US

Inventors

• Parvesh Sharma · Gainesville, US
• Brij M. Moudgil · Ontario, US
• Glenn A. Walter · Gainesville, US
• Stephen Grobmyer · Shaker Heights, US
• Swadeshmukul Santra · Orlando, US
• Huabei Jiang · Gainesville, US
• Scott C. Brown · Warsaw, US
• Edward W. Scott · Culver City, US
• Qizhi Zhang · Gainesville, US
• Niclas Bengtsson · Gainesville, US

Key dates

• Filing date: Dec 28, 2012
• Grant date: Dec 31, 2013
• Expiry date: Dec 28, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61B6/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Multimodal nanoparticles are nanoparticles containing contrast agents for PAT and one or more of luminescence imaging, x-ray imaging, and/or MRI. The multimodal nanoparticles can have a dielectric core comprising an oxide with a metal coating on the core. The particles can be metal speckled. The multimodal nanoparticles can be used for therapeutic purposes such as ablation of tumors or by neutron capture in addition to use as contrast agents for imaging.