Patent · US Active

Method for producing L-phenylephrine using an alcohol dehydrogenase of Aromatoleum aromaticum EBN1 (Azoarcus sp. EBN1)

US8617854B2 · kind B2 · utility

1Cited by

4References

12Claims

0Family size

Assignee

BASF SE

Inventors

Michael Breuer · Darmstadt, DE
Andreas Pletsch · Schifferstadt, DE
Bernhard Hauer · Neheim, DE
Wolfgang Siegel · Schifferstadt, DE

Key dates

Filing date	Sep 15, 2009
Grant date	Dec 31, 2013
Priority date	—
Expiry date	Sep 15, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12P7/22
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to a multi-stage process for producing substituted, optically active alcohols, comprising an enzyme-catalyzed synthesis step, in particular a synthesis step which is catalyzed by an alcohol dehydrogenase. The inventive method is particularly suitable for producing phenylephrine, i.e. 3-[(1R)-1-hydroxy-2-methylamino-ethyl]-phenol.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.