Cyclosporin derivatives

US8618065B2 · kind B2 · utility

Assignee

• Max-Planck-Gesellschaft zur Föderung der Wissenschaften e.V. · US

Inventors

• Gunter Fischer · Hamburg, DE
• Miroslav Malesevic · Bodenwerder, DE
• Frank Erdmann · Bodenwerder, DE
• Jan Kühling · Bodenwerder, DE
• Michael Bukrinsky · Glenwood Landing, US
• Stephanie Constant · Herndon, US

Key dates

• Filing date: Feb 15, 2012
• Grant date: Dec 31, 2013
• Expiry date: Feb 15, 2032

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/55
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A cyclosporin derivative of general Formula (I) or a pharmaceutically compatible salt thereof, which have a pharmaceutical effectiveness, for example in the case of chronic inflammatory diseases. The cyclosporin derivatives are preferably free from a peptide section capable of passing through the membrane of a biological cell.