Ligand libraries for screening GPCRs
US8618283B2 · kind B2 · utility
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12Claims
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Assignee
Inventors
Key dates
| Filing date | Nov 4, 2011 |
| Grant date | Dec 31, 2013 |
| Priority date | — |
| Expiry date | Nov 4, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D281/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides compounds of general formulae (I)-(IV) or pharmaceutically acceptable salts thereof:The invention also provides methods of preparing the compounds, pharmaceutical compositions comprising the compounds and use of the compounds for the preparation of medicaments intended to modulate the activity of one or more members of the G-protein coupled receptor (GPCR) class. Compounds of the invention may be used to create a compound library for use in screening for agents which modulate signalling through GPCRs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.