Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity
US8618286B2 · kind B2 · utility
1Cited by
3References
26Claims
0Family size
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Key dates
| Filing date | Jan 27, 2012 |
| Grant date | Dec 31, 2013 |
| Priority date | — |
| Expiry date | Jan 27, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention features benzoxazines, benzothiazines, and related compounds that inhibit nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms. Exemplary compounds are of the formula:The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing various medical conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.