Patent · US Active

Fosaprepitant dimeglumine intermediate, neutral fosaprepitant, and amorphous fosaprepitant dimeglumine and processes for their preparations

US8623844B2 · kind B2 · utility

4Cited by

1References

12Claims

0Family size

Inventors

Navin Ganesh Bhatt · Navi Mumbai, IN
Nikhil Trivedi · Navi Mumbai, IN
Mahesh Khedekar · Thane, IN
Sukumar Sinha · Mumbai, IN
Mubeen Ahmed Khan · Navi Mumbai, IN
Ramjilal Yadav · Navi Mumbai, IN

Key dates

Filing date	Jul 17, 2009
Grant date	Jan 7, 2014
Priority date	—
Expiry date	Mar 13, 2030

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P39/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention generally relates to a process for the preparation of fosaprepitant dimeglumine intermediate and its use in the preparation of fosaprepitant dimeglumine; to a neutral form of fosaprepitant in a solid state and processes for the preparation thereof; and to a stable amorphous fosaprepitant dimeglumine, having a stability at temperatures of about 2° C. to about 8° C. and at a relative humidity below at least 60%; and a process for the preparation thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.