Treatment of cancers characterized by chromosomal rearrangement of the NUT gene
US8623853B2 · kind B2 · utility
0Cited by
31References
20Claims
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Key dates
| Filing date | Jul 21, 2009 |
| Grant date | Jan 7, 2014 |
| Priority date | — |
| Expiry date | Jul 21, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed, inter alia, to methods of treating NUT midline carcinoma (NMC) by administering compounds that promote increased histone acetylation. The invention also includes assay methods for determining the responsiveness of NMC to specific histone deacetylases and other compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.