Pyridino-pyridinone derivatives, preparation and therapeutic use thereof
US8623893B2 · kind B2 · utility
14Cited by
3References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 22, 2012 |
| Grant date | Jan 7, 2014 |
| Priority date | — |
| Expiry date | May 22, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to derivatives of pyridino-pyridinones, and to their preparation and use thereof, having activity as inhibitors of kinase activity of receptors for PDGF (platelet derived growth factors) ligands and optionally of receptors for the FLT3 (fms-like tyrosine kinase receptor) ligand receptors, said derivatives comprising compounds of formula (I):wherein the various substituent groups are more specifically defined herein. The compounds are suitable as therapeutics for the treatment of various proliferative diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.