Lipidated imidazoquinoline derivatives
US8624029B2 · kind B2 · utility
7Cited by
2References
2Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 23, 2009 |
| Grant date | Jan 7, 2014 |
| Priority date | — |
| Expiry date | Aug 17, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/55511
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The compounds of the subject invention are adjuvant molecules that comprise a imidazoquinoline molecule covalently linked to a phospho- or phosphonolipid group. The compounds of the invention have been shown to be inducers of interferon-a, IL-12 and other immunostimulatory cytokines and possess an improved activity profile in comparison to known cytokine inducers when used as adjuvants for vaccine antigens.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.