Patent · US Active

N-demethylation of 6-keto morphinans

US8624030B2 · kind B2 · utility

1Cited by
1References
15Claims
0Family size

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Inventors

Key dates

Filing dateAug 3, 2011
Grant dateJan 7, 2014
Priority date
Expiry dateApr 25, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D489/02
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention provides processes for the demethylation of an N-methyl morphinan comprising a ketone functional group. In particular, the invention provides methods for the protection of the ketone functional group such that impurities are not generated during the demethylation of the N-methyl morphinan.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.